Prescription Drugs

ALPRAZOLAM (Alprazolam) Tablet, Orally Disintegrating ALPRAZOLAM (Alprazolam) Tablet, Orally Disintegrating [Par Pharmaceutical Inc.]

admin — Fri, 12 Mar 2010 18:20:13 +0000

Updated Date: Mar 11, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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ALPRAZOLAM (Alprazolam) Tablet, Orally Disintegrating ALPRAZOLAM (Alprazolam) Tablet, Orally Disintegrating [Par Pharmaceutical Inc.] is a post from: Prescription Drugs

sanofi-aventis Successfully Completes the Acquisition of Chattem, Inc.

admin — Fri, 12 Mar 2010 18:20:12 +0000

ARIS, France, March 11 (HSMN NewsFeed) – sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced today that it has completed its acquisition of 100% of Chattem, Inc., which is now a wholly-owned subsidiary of the sanofi-aventis Group.

By strengthening it… Biopharmaceuticals, Mergers & Acquisitionssanofi-aventis, Chattem, Allegra, fexofenadine (Source: HSMN NewsFeed)

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sanofi-aventis Successfully Completes the Acquisition of Chattem, Inc. is a post from: Prescription Drugs

Effect of Piperine, a Major Component of Black Pepper, on the Intestinal Absorption of Fexofenadine and Its Implication on Food–Drug Interaction

admin — Fri, 12 Mar 2010 18:20:12 +0000

In conclusion, piperine significantly enhanced the oral exposure of fexofenadine in rats likely by the inhibition of P-glycoprotein-mediated cellular efflux during the intestinal absorption, suggesting that the combined use of piperine or piperine-containing diet with fexofenadine may require close monitoring for potential drug[ndash]diet interactions. (Source: Journal of Food Science) Effect of Piperine, a Major Component of Black Pepper, on the Intestinal Absorption of Fexofenadine and Its Implication on Food–Drug Interaction is a post from: Prescription Drugs

Effect of Piperine, a Major Component of Black Pepper, on the Intestinal Absorption of Fexofenadine and Its Implication on Food–Drug Interaction is a post from: Prescription Drugs

DUONEB (Ipratropium Bromide And Albuterol Sulfate) Solution [Dey, LP]

admin — Fri, 12 Mar 2010 18:20:08 +0000

Updated Date: Mar 11, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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DUONEB (Ipratropium Bromide And Albuterol Sulfate) Solution [Dey, LP] is a post from: Prescription Drugs

Regular Analgesic Use May Increase Risk for Hearing Loss

admin — Fri, 12 Mar 2010 17:00:36 +0000

Regular use of aspirin, acetaminophen, and nonsteroidal anti-inflammatory drugs may increase the risk for hearing loss in men, particularly those younger than 60 years. Medscape Medical News (Source: Medscape Today Headlines) Regular Analgesic Use May Increase Risk for Hearing Loss is a post from: Prescription Drugs

Regular Analgesic Use May Increase Risk for Hearing Loss is a post from: Prescription Drugs

FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

admin — Fri, 12 Mar 2010 17:00:36 +0000

Abstract Hepatotoxicity from paracetamol is of great concern because of the considerable number of patients who develop severe toxicity
from this drug. A group of senior medical practitioners, academics and scientists were brought together on June 29 and 30,
2009 by the Food and Drug Administration of USA (FDA) with the aim of providing advice on how to limit the number of cases
of hepatotoxicity due to paracetamol in USA. The most contentious recommendations were the reduction in the dose of paracetamol
to 650 mg and the elimination of prescription combination products of paracetamol and opiates. The first recommendation indicates
that many members of the committee consider, despite much evidence to the contrary, that therapeutic doses of paracetamol
(up to 4 g daily) are…

FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable? is a post from: Prescription Drugs

Regular Analgesic Use Linked to Hearing Loss in Men

admin — Fri, 12 Mar 2010 17:00:36 +0000

The regular use of aspirin, acetaminophen, and nonsteroidal anti-inflammatory drugs may increase the risk of hearing loss in men, especially younger men, according to research published in the March issue of the American Journal of Medicine. (Source: Modern Medicine) Regular Analgesic Use Linked to Hearing Loss in Men is a post from: Prescription Drugs

Regular Analgesic Use Linked to Hearing Loss in Men is a post from: Prescription Drugs

The Influence of Ondansetron on the Analgesic Effect of Acetaminophen After Laparoscopic Hysterectomy.

admin — Fri, 12 Mar 2010 17:00:36 +0000

Authors: Jokela R, Ahonen J, Seitsonen E, Marjakangas P, Korttila K
The 5-HT(3) antagonists tropisetron and granisetron have been shown to block the analgesic effect of acetaminophen in healthy volunteers. To study the interaction between ondansetron and acetaminophen in women undergoing laparoscopic hysterectomy, we randomized 134 patients into three groups to receive acetaminophen-placebo (AP), acetaminophen-ondansetron (AO), or placebo-placebo (PP). One gram of intravenous acetaminophen or placebo was administered at the induction of anesthesia and every 6 h thereafter for 24 h, and 4 mg of ondansetron or placebo was administered at the end of surgery. Pain control was provided by patient-controlled analgesia (PCA)-oxycodone. Acetaminophen (as compared to placebo) in periodic doses …

The Influence of Ondansetron on the Analgesic Effect of Acetaminophen After Laparoscopic Hysterectomy. is a post from: Prescription Drugs

ALLEGRA D-12 HOUR (Fexofenadine Hydrochloride And Pseudoephedrine Hydrochloride) Tablet, Extended Release [Sanofi-Aventis U.S. LLC]

admin — Thu, 11 Mar 2010 19:40:10 +0000

Updated Date: Mar 10, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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ALLEGRA D-12 HOUR (Fexofenadine Hydrochloride And Pseudoephedrine Hydrochloride) Tablet, Extended Release [Sanofi-Aventis U.S. LLC] is a post from: Prescription Drugs

Clinical and Virologic Efficacy of Herpes Simplex Virus Type 2 Suppression by Acyclovir in a Multicontinent Clinical Trial

admin — Thu, 11 Mar 2010 04:40:39 +0000

The Journal of Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles.

Acyclovir suppressive therapy (400 mg twice daily) reduces herpes simplex virus (HSV) type 2–associated genital ulcer disease and lesional HSV shedding. In an international trial of acyclovir for suppression of HSV type 2 to prevent human immunodeficiency virus (HIV) acquisition (HIV Prevention Trials Network 039), acyclovir had a smaller effect on the frequency of genital ulcer disease as well as a smaller effect on the frequency and quantity of lesional HSV DNA in African women and Peruvian men, compared with its effects in men in the United States. The observed regional variation in the clinical and virologic efficacy of acyclovir for HSV suppression warrants further evaluation of determinants of r…

Clinical and Virologic Efficacy of Herpes Simplex Virus Type 2 Suppression by Acyclovir in a Multicontinent Clinical Trial is a post from: Prescription Drugs