Prescription Drugs 2 Go

Authors: Smith SM, Gums JG
Influenza infection is annually responsible for significant morbidity and mortality, particularly among the very young and old. Recently updated guidelines recommend influenza vaccination of all children aged 6 months to 18 years; however, childhood vaccination remains underutilized. Furthermore, concerns over the reduced efficacy of vaccination in children have further heightened the need for effective treatment schemes. Antiviral therapies have emerged as attractive options in the battle against influenza infection. These agents include the adamantanes (amantadine and rimantadine) and neuraminidase inhibitors (zanamivir, oseltamivir, …

We report the association of ipsilateral trigemino-autonomic headache to a case of right-sided nuclear facial and abducens
palsy (Gasperini syndrome), ipsilateral hypacusis and right hemiataxia, caused by the occlusion of the right anterior inferior
cerebellar artery. Short-lasting attacks of mild to moderate ipsilateral fronto-periorbital head pain, accompanied by lacrimation
and mild conjunctival injection during more severe attacks, were present from the onset of symptoms, with a gradual worsening
over the next few months and remitting during naproxen therapy. Magnetic resonance imaging showed an infarct in the right
cerebellar peduncle, extending …

In experimental animal and cell culture models, activation of peroxisome proliferator-activated receptor (PPAR) in heart has been shown to have beneficial effects on cardiac function and cardiomyocyte physiology. The goal of this study was to identify the signaling pathway by which PPAR activation protects cardiomyocytes from the deleterious effects of hypertrophic stimuli. In primary cardiomyocyte cultures, we found that genetic or pharmacological activation of PPAR protected cells from cardiac hypertrophy induced by -adrenergic stimulation. Examination of gene expression in these cells revealed a surprising increase in the expression of adiponectin …

There is no associated increased risk of major birth defects for mothers who are exposed to the antiviral drugs acyclovir, valacyclovir, and famciclovir in their first trimester of pregnancy, a Danish study has found. (Source: Nursing Times Breaking News)

Authors: Karina G Zecchin, Franco A Rossato, Helena F Raposo, Daniela R Melo, Luciane C Alberici, Helena CF Oliveira, Roger F Castilho, Ricardo D Coletta, Aníbal E Vercesi
& Edgard Graner (Source: Laboratory Investigation AOP)

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Aim: (Source: Diabetes, Obesity and Metabolism)

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An analysis of data from Denmark finds no associated increased risk of major birth defects for mothers who were exposed during the first trimester of pregnancy to the antiviral drugs acyclovir, valacyclovir, and famciclovir, often used to treat herpes simplex and herpes zoster infections, according to a study in the August 25 issue of JAMA. The prevalence of herpes simplex is high, and more than 1 percent of susceptible women acquire herpes simplex during the first trimester of pregnancy, with antiviral treatment indicated for a significant number of women …

A 52-year-old woman sought help for intractable lumbosacral pain, which began after she lifted a heavy object and fell onto her back more than 2 decades ago. Additional symptoms included burning, numbness, tingling, and pain in her right hip, posterior thigh, leg, and toes, and diminished sensation and sensitivity throughout her right leg and foot. Muscle spasms/cramps, which often interrupted sleep, were intermittently present in her right buttock and right lower extremity. Right-foot drop impaired her ability to walk, and she used a wheeled walker with a seat because she …

Updated Date: Aug 27, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Updated Date: Aug 27, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))