Meta-Analysis of the Efficacy and Safety of Naproxen Sodium in the Acute Treatment of Migraine
6 March 2010
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Conclusions.[mdash] The available evidence suggests that naproxen sodium is more effective but may cause more adverse events than placebo in the acute treatment of moderate to severe migraine. It is effective in reducing headache intensity, rendering pain-free at 2 hours and improving migraine-associated symptoms. However, its effectiveness relative to other active comparators needs to be better defined by appropriate head-to-head clinical trials. (Headache 2010;[bull][bull]:[bull][bull]-[bull][bull]) (Source: Headache: The Journal of Head and Face Pain)
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