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Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs.

8 March 2010 53 views No Comment

Authors: Dapat C, Suzuki Y, Saito R, Kyaw Y, Myint YY, Lin N, Oo HN, Oo KY, Win N, Naito M, Hasegawa G, Dapat IC, Zaraket H, Baranovich T, Nishikawa M, Saito T, Suzuki H
In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.
PMID: 20202427 [PubMed - as supplied by publisher] (Source: Emerging Infectious Diseases)

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