Prescription Drugs 2 Go

Patients with chronic kidney disease treated with Benazepril (Lotensin) plus amlodipine (Norvasc) were less likely to experience worsening renal function than those treated with Benazepril plus hydrochlorothiazide, researchers found. (Source: MedPage Today Cardiovascular)

GPs should consider Benazepril plus amlodipine for high blood pressure, say US researchers. (Source: Pulse)

Using Benazepril in combination with amlodipine could slow chronic kidney disease (CKD) progression, according to international researchers. (Source: Nursing Times Breaking News)

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Initial antihypertensive therapy with the combination of Benazepril and amlodipine slows progression of nephropathy to a greater extent than does the combination of Benazepril and hydrochlorothiazide, conclude the ACCOMPLISH trial investigators. (Source: MedWire News – Hypertension)

In hypertensive patients with high cardiovascular risk, Benazepril and amlodipine are better at
reducing progression of chronic kidney disease than Benazepril with hydrochlorothiazide, according to research
published online Feb. 18 in The Lancet. (Source: Modern Medicine)

Source: Lancet
Area: News
Secondary analysis of the ACCOMPLISH trial suggests that in high-risk patients, combining a calcium-channel blocker (CCB) rather than a diuretic with an ACE-inhibitor reduces progression of nephropathy. An accompanying Comment, however, advises caution in interpreting the results, as they are unexpected and the outcome used is problematic.
 
ACCOMPLISH was a large (n=11,506) randomised controlled trial that compared Benazepril (a standard ACE-inhibitor no longer marketed in the UK) plus amlodipine with Benazepril plus hydrochlorothiazide in patients with hypertension who were at high risk for cardiovascular events. Primary …

Initial antihypertensive therapy with the combination of Benazepril and amlodipine slows progression of nephropathy to a greater extent than does the combination of Benazepril and hydrochlorothiazide, conclude the ACCOMPLISH trial investigators. (Source: MedWire News – Cardiology)

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(Source: Physician’s First Watch current issue)

Heartwire (Source: Medscape Medical News Headlines)

An analysis of the ACCOMPLISH study showed that after a mean follow-up of three years, amlodipine and Benazepril significantly reduced the progression to chronic kidney disease 48%, an absolute…
For complete story visit theheart.org. (Source: theHeart.org)