Prescription Drugs 2 Go

Authors: Mukae H, Urabe K, Yanagihara K, Ishimoto H, Sakamoto N, Ishii H, Nakayama S, Ishimatsu Y, Abe K, Shirai R, Kohno S
Pseudomonas (P.) aeruginosa frequently colonizes the respiratory tract of patients with chronic respiratory tract infections such as diffuse panbronchiolitis (DPB). The number of dendritic cells (DCs) that play a central role in immune functions as antigen-presenting cells is reportedly increased in the bronchiolar tissues of patients with DPB. However, the functions of DCs in chronic P. aeruginosa respiratory tract infection have not been defined. …

Source: Manufacturer notification
Area: Other Library Updates > SPC Changes
SPCs have been updated to include new recommendations for patients on concomitant verapamil or clarithromycin, based on drug-drug interactsion studies in healthy adults. 
Plasma concentrations of dabigatran might be elevated when co-administered with strong P-glycoprotein inhibitors eg verapamil, amiodarone.
Dosing should be reduced to 150mg daily in patients receiving concomitant verapamil.  If patients are also renally impaired, a reduction to 75mg should be considered.
For patients on concomitant dabigatran and clarithromycin the SPC recommends close monitoring for signs of bleeding, without …

Authors: Lee SH, Min JW, Um SW, Han SS, Han SK, Shim YS, Yim JJ
Mycobacterium abscessus (M. abscessus) is the second most common nontuberculous mycobacteria (NTM) in South Korea. Nevertheless, the diagnosis and treatment of M. abscessus lung disease can be problematic. Surgical resection has been tried for patients with localized M. abscessus lung disease refractory to medical treatment. Here, we report on a 25-year-old woman with M. abscessus lung disease who had been diagnosed and treated three times for pulmonary tuberculosis. She was initially diagnosed …

Conclusion:</b> One week of furazolidone in combination with 2 weeks of amoxicillin, omeprazole, and bismuth subcitrate is a safe and cost-effective regimen for the eradication of <i>H pylori</i>. Adding metronidazole to the above regimen does not increase the eradication rate. (Source: The Saudi Journal of Gastroenterology)

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(NaturalNews) The entire pharmaceutical industry is based on the idea that for whatever’s wrong with you, there’s a patented chemical pill that can make it better. Feeling some anxiety? There’s a pill for that. Have high blood pressure? There’s a pill for that, too. Suffering from sleepless nights? There’s yet another pill for that, too.Importantly, modern medicine and the pharmaceutical industry both believe there is no limit to how many prescription medications you can simultaneously take. If you have ten health problems, they’ve got ten different pills for you. And …

Abstract  Adult-onset Still’s disease (AOSD) is a rare rheumatological condition characterized by an acute systemic involvement. There
are no treatment guidelines. Glucocorticoids (GC), methotrexate (MTX), cyclosporin A and biologic agents have been successfully
used, often in association. We treated six cases of AOSD with clarithromycin (CM) in combination with low-mild dose of GC
and MTX. Four of them were not responsive to high-dose GC added to DMARDs, while two of them were treated with low-mild dose
of GC added to CM from the beginning. CM, 500 mg b.i.d., was added to a …

Abstract  We evaluated the β-lactamase-producing ability and resistance to 20 antibacterial agents of 448 clinically isolated strains
of Haemophilus influenzae accumulated from October 2000 to July 2001 (phase 1) and of 376 different strains accumulated from January to June 2004 (phase
2), from institutions that participated in a nationwide Drug-Resistant Pathogen Surveillance Group in Pediatric Infectious
Disease. Between phase 1 and phase 2 the proportion of β-lactamase-negative ampicillin (ABPC)-susceptible (BLNAS) strains
declined from 62.9% to 34.3%; the proportions of β-lactamase-positive ABPC-resistant (BLPAR) strains were 8.3% and 6.4% in
phases 1 and …

Conclusions
The impact of associations among macrolide consumption, influenza and socioeconomic factors may reflect inappropriate use of these agents to treat viral infections and/or prescribing for secondary infections, and knowledge of the virus versus bacteria problem and accessibility of healthcare. Further research surrounding differences in access to antimicrobial prescriptions and treatment options between advantaged and disadvantaged populations is suggested to further understand the dynamics of antimicrobial use in Canada. (Source: Journal of Antimicrobial Chemotherapy)

MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed – …

(Source: Reactions)

Abstract: Toxoplasma gondii is a worldwide zoonotic infection. The sexual cycle occurs only in the cat family: only the cat’s faeces are infectious; but cysts in animals and birds can cause infection when these are consumed. Acquired acute toxoplasma infection can be asymptomatic or have nonspecific flu-like symptoms. Lymphadenopathy is the most recognized presentation and may last more than six months. Retinochoroiditis is usually a result of reactivated congenital infection. Increasingly recognized is chronic infection producing a chronic fatigue syndrome. Reactivated infections, especially in the immunocompromised, are a major problem …