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CLINDAMYCIN HYDROCHLORIDEcapsule [Watson Laboratories, Inc.]

admin — Fri, 10 Sep 2010 08:00:04 +0000

Updated Date: Sep 7, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST)) CLINDAMYCIN HYDROCHLORIDEcapsule [Watson Laboratories, Inc.] is a post from: Prescription Drugs

CLINDAMYCIN HYDROCHLORIDEcapsule [Watson Laboratories, Inc.] is a post from: Prescription Drugs

Clindamycin: Acute oedema of the larynx: 2 case reports

admin — Fri, 10 Sep 2010 08:00:04 +0000

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Clindamycin: Acute oedema of the larynx: 2 case reports is a post from: Prescription Drugs

Dangerous drug interactions leading to hemolytic uremic syndrome following lung transplantation

admin — Fri, 10 Sep 2010 07:40:32 +0000

Conclusions: There are 21 cases of HUS following lung transplantation in the literature that may have been induced by high tacrolimus levels.Macrolides in patients taking Cyclosporin or Tacrolimus lead to high levels. Mechanism of action could be glomeruloconstrictor effect with reduced GFR increased production of Endothelin-1 and increased Platelet aggregation. (Source: Journal of Cardiothoracic Surgery) Dangerous drug interactions leading to hemolytic uremic syndrome following lung transplantation is a post from: Prescription Drugs

Dangerous drug interactions leading to hemolytic uremic syndrome following lung transplantation is a post from: Prescription Drugs

[Case Report] Dangers in the garden

admin — Fri, 10 Sep 2010 07:40:32 +0000

In March, 2010, a previously fit and healthy 67-year-old man presented with an 8-day history of fever with rigors, intermittent confusion, lethargy, and shortness of breath. On admission, he was febrile with a temperature of 39°C and had clinical signs of a left-sided pneumonia, accompanied by general abdominal tenderness. His white blood cell count was 14·8×109/L (number of neutrophils was 11·3×109/L, and lymphocyles 0·2×109/L), and C-reactive protein concentration was raised at 475 mg/L. Renal, and liver function were abnormal: urea concentration was 21·6 mmol/L; creatinine 257 μmol/L; sodium 135 mmol/L; potassium 4 mmol/L; aspartate aminotransferase 115 IU/L; alanine aminotransferase 80 IU/L; and bilirubin 56 μmol/L. A chest radiograph showed complete opacification of his left…

[Case Report] Dangers in the garden is a post from: Prescription Drugs

Clarithromycin attenuates autophagy in myeloma cells.

admin — Fri, 10 Sep 2010 07:40:32 +0000

Authors: Nakamura M, Kikukawa Y, Takeya M, Mitsuya H, Hata H
It has been reported that Clarithromycin (CAM) augments the anti-tumor activity of thalidomide against multiple myeloma (MM) cells, while the mechanism remains unclear. A myeloma cell line or primary myeloma cells were treated with CAM. Autophagy was analyzed by morphological changes, LC3 expression and lysotracker staining. CAM induced vacuoles in the cytoplasm of MM cells which resembled autolysosomes. The manifestation of the CAM-induced vacuoles was blocked by treatment with PI3-kinase inhibitor. CAM induced an accumulation of LC3-II without affecting the mTOR or AKT pathways, eventually leading to cell death. CAM may halt the autophagy process after fusion of autophagosomes with lysosomes. This phenomenon may explain how…

Clarithromycin attenuates autophagy in myeloma cells. is a post from: Prescription Drugs

Clarithromycin/ergotamine interaction: Arterial vasospasm: case report

admin — Fri, 10 Sep 2010 07:40:32 +0000

(Source: Reactions) MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising. Clarithromycin/ergotamine interaction: Arterial vasospasm: case report is a post from: Prescription Drugs

Clarithromycin/ergotamine interaction: Arterial vasospasm: case report is a post from: Prescription Drugs

Activity of high dose daptomycin, vancomycin and moxifloxacin alone or in combination with clarithromycin or rifampin in a novel in vitro model of Staphylococcus aureus biofilm.

admin — Fri, 10 Sep 2010 07:40:31 +0000

In conclusion, we developed a novel in-vitro PK/PD model to assess the activity of antimicrobials against mature bacterial biofilm. Combinations of DAP or MOX with CLA were the most effective regimens and may represent promising options to treat persistent infections caused by S. aureus biofilms. PMID: 20696880 [PubMed - as supplied by publisher] (Source: Antimicrobial Agents and Chemotherapy) Activity of high dose daptomycin, vancomycin and moxifloxacin alone or in combination with clarithromycin or rifampin in a novel in vitro model of Staphylococcus aureus biofilm. is a post from: ...

Activity of high dose daptomycin, vancomycin and moxifloxacin alone or in combination with clarithromycin or rifampin in a novel in vitro model of Staphylococcus aureus biofilm. is a post from: Prescription Drugs

Clarithromycin attenuates myocardial ischemia–reperfusion injury

admin — Fri, 10 Sep 2010 07:40:31 +0000

Expert Opinion on Therapeutic Targets, Volume 14, Issue 9, Page 881-893, September 2010. (Source: Expert Opinion: Expert Opinion on Therapeutic Targets: Table of Contents) Clarithromycin attenuates myocardial ischemia–reperfusion injury is a post from: Prescription Drugs

Clarithromycin attenuates myocardial ischemia–reperfusion injury is a post from: Prescription Drugs

Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study.

admin — Fri, 10 Sep 2010 07:40:31 +0000

Conclusion: local data regarding the primary resistance of H. pylori to Clarithromycin, metronidazole and amoxicillin and the main genetic mutation involved in Clarithromycin resistance in vivo (A2143G) are necessary to prove a clear need for a periodic evaluation of antibiotic consumption and new therapeutic strategies in Tunisia in order to avoid the emergence of resistant strains. (Source: Annals of Clinical Microbiology and Antimicrobials) Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study. is a post from: Prescription Drugs

Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study. is a post from: Prescription Drugs

[Review] Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

admin — Fri, 10 Sep 2010 07:40:31 +0000

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally thought to have high mortality rates. However, many cases can be treated with the right combination and rational use of available antituberculosis drugs. This Review describes the evidence available for each drug and discusses the basis for recommendations for the treatment of patients with MDR and XDR tuberculosis. The recommended regimen is the combination of at least four drugs to which the Mycobacterium tuberculosis isolate is likely to be susceptible. Drugs are chosen with a stepwise selection process through five groups on the basis of efficacy, safety, and cost. Among the first group (the oral first-line drugs) high-dose isoniazid, pyrazinamide, and ethambutol are thought of as an adjunct for t…

[Review] Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis is a post from: Prescription Drugs